Metabolic Regulation of Insulin Secretion

Regulation of metabolic fuel homeostasis is a critical function of b-cells, which are located in the islets of Langerhans of the animal pancreas. Impairment of this b-cell function is a hallmark of pancreatic b-cell failure and may lead to development of type 2 diabetes mellitus. b-Cells are essenti...

Full description

Bibliographic Details
Main Authors: Keane, Kevin, Newsholme, Philip
Other Authors: Gerald Litwack
Format: Book Chapter
Published: Academia Press 2014
Online Access:http://hdl.handle.net/20.500.11937/39539