The influence of bile salts on the distribution of simvastatin in the octanol/buffer system

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The influence of bile salts on the distribution of simvastatin in the octanol/buffer system

INTRODUCTION: Distribution coefficient (D) is useful parameter for evaluating drugs permeability properties across biological membranes, which are of importance for drugs bioavailability. Given that bile acids are intensively studied as drug permeation-modifying and -solubilizing agents, the aim of...

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Bibliographic Details
Main Authors:	Đanić, M., Pavlović, N., Stanimirov, B., Vukmirović S, Nikolic, K., Agbaba, D., Mikov, Momir
Format:	Journal Article
Published:	Informa Healthcare 2016
Online Access:	http://hdl.handle.net/20.500.11937/39358

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