The influence of bile salts on the distribution of simvastatin in the octanol/buffer system
INTRODUCTION: Distribution coefficient (D) is useful parameter for evaluating drugs permeability properties across biological membranes, which are of importance for drugs bioavailability. Given that bile acids are intensively studied as drug permeation-modifying and -solubilizing agents, the aim of...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Published: |
Informa Healthcare
2016
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| Online Access: | http://hdl.handle.net/20.500.11937/39358 |