Garcinol, a polyisoprenylated benzophenone modulates multiple proinflammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma

Constitutive activation of proinflammatory transcription factors such as STAT3 and NF-kB plays a pivotal role in the proliferation and survival of squamous cell carcinoma of the head and neck (HNSCC). Thus, the agents that can modulate deregulated STAT3 and NF-kB activation have a great potential bo...

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Bibliographic Details
Main Authors: Li, F., Shanmugam, M., Chen, L., Chatterjee, S., Basha, J., Kumar, Alan Prem, Kundu, T., Sethi, G.
Format: Journal Article
Published: American Association for Cancer Research 2013
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/39026