Binding mode analysis of dual inhibitors of human thymidylate synthase and dihydrofolate reductase as antitumour agents via molecular docking and DFT studies

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Binding mode analysis of dual inhibitors of human thymidylate synthase and dihydrofolate reductase as antitumour agents via molecular docking and DFT studies

Due to the diligence of inherent redundancy and robustness in many biological networks and pathways, multitarget inhibitors present a new prospect in the pharmaceutical industry for treatment of complex diseases. Nevertheless, to design multitarget inhibitors is concurrently a great challenge for me...

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Bibliographic Details
Main Authors:	Arooj, Mahreen, Lee, K.
Format:	Journal Article
Published:	Taylor and Francis Ltd. 2015
Online Access:	http://hdl.handle.net/20.500.11937/3898

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