The effect of a single nucleotide polymorphismof the CYP4F2 gene on blood pressure and 20-hydroxyeicosatetraenoic acidexcretion after weight loss

Background: Genetic background partly determines the efficacy of interventions to lower blood pressure (BP). The CYP4F2 and CYP4A11 enzymes are renal 20-hydroxyeicosatetraenoic acid (20-HETE) synthases that regulate BP. Gene variants of CYP4F2 and CYP4A11 associate with hypertension and stroke. We s...

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Bibliographic Details
Main Authors: Ward, Natalie, Croft, K., Puddey, I., Phillips, M., van Bockxmeer, F., Beilin, L., Barden, A.
Format: Journal Article
Published: 2014
Online Access:http://hdl.handle.net/20.500.11937/38490