PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis

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PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis

Studies employing mouse models have identified crypt base and position +4 cells as strong candidates for intestinal epithelial stem cells. Equivalent cell populations are thought to exist in the human intestine; however robust and specific protein markers are lacking. Here, we show that in the human...

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Bibliographic Details
Main Authors:	Sakthianandeswaren, A., Christie, M., D'Andreti, C., Tsui, C., Jorissen, R., Li, S., Fleming, N., Gibbs, P., Lipton, L., Malaterre, J., Ramsay, R., Phesse, T., Ernst, M., Jeffery, R., Poulsom, R., Leedham, S., Segditsas, S., Tomlinson, I., Bernhard, O., Simpson, R., Walker, F., Faux, M., Church, N., Catimel, B., Flanagan, D., Vincan, Elizabeth, Sieber, O.
Format:	Journal Article
Published:	2011
Online Access:	http://hdl.handle.net/20.500.11937/38391

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