IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice

The role of macrophages and their interactions with T cells during aging is not well understood. We determined if activating elderly-derived macrophages could rescue age-related and tumor-induced T cell dysfunction. Healthy elderly (18–24 months) Balb/c contained significantly more splenic IL-10-sec...

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Bibliographic Details
Main Authors: Jackaman, Connie, Dye, Danielle, Nelson, Delia
Format: Journal Article
Published: Springer Netherlands 2014
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/3766