Hypoxia prolongs monocyte/macrophage survival and enhanced glycolysis is associated with their maturation under aerobic conditions
In chronic inflammatory lesions macrophages are abundant and adapt to the low oxygen concentrations often present there. In low oxygen some cell types die by apoptosis, as reported for macrophage cell lines, while others survive better as they shift their metabolism to anaerobic glycolysis. It was f...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Published: |
American Association of Immunologists
2009
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| Online Access: | http://hdl.handle.net/20.500.11937/37597 |