Analysis of selective metal-salt-induced endotoxin precipitation in plasmid DNA purification using improved limulus amoebocyte lysate assay and central composite design
Recent advancements in plasmid DNA (pDNA) production involve the development of innovative and cost-effective methods as well as reduced number of unit operations. This study investigates the feasibilities of using a metal salt to selectively remove endotoxins from clarified cell lysates containing...
| Main Authors: | , |
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| Format: | Journal Article |
| Published: |
American Chemical Society
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/36784 |