Pharmacokinetic comparison of two piperaquine-containing artemisinin combination therapies in Papua New Guinean children with uncomplicated malaria

Pharmacokinetic differences between piperaquine (PQ) base and PQ tetraphosphate were investigated in 34 Papua New Guinean children aged 5 to 10 years treated for uncomplicated malaria with artemisinin-PQ (ART-PQ) base or dihydroartemisinin-PQ (DHA-PQ) tetraphosphate. Twelve children received ART-PQ...

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Bibliographic Details
Main Authors: Salman, S., Page-Sharp, Madhu, Batty, Kevin, Kose, K., Griffin, S., Siba, P., Ilett, K., Mueller, I., Davis, T.
Format: Journal Article
Published: American Society for Microbiology 2012
Online Access:http://hdl.handle.net/20.500.11937/36228