Doxorubicin-induced death in tumour cells and cardiomyocytes: is autophagy the key to improving future clinical outcomes?

Objectives: Doxorubicin, a commonly used frontline chemotherapeutic agent for cancer, is not without side-effects. The original thinking that the drug causes necrosis in tumours has largely given way to its link with apoptosis over the past two decades. Key findings: More recently, major biomarkers...

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Bibliographic Details
Main Authors: Tacar, O., Dass, Crispin
Format: Journal Article
Published: John Wiley & Sons Ltd. 2013
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/36210