Characterization of Maleimide-Based Glycogen Synthase Kinase-3 (GSK-3) Inhibitors as Stimulators of Steroidogenesis

Inhibition of GSK-3β has been well documented to account for the behavioral actions of the mood stabilizer lithium in various animal models of mood disorders. Recent studies have showed that genetic or pharmacological inhibition of GSK-3β resulted in anxiolytic-like and pro-social behavior. In our o...

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Bibliographic Details
Main Authors: Gunosewoyo, Hendra, Midzak, A., Gaisina, I., Sabath, E., Fedolak, A., Hanania, T., Brunner, D., Papadopoulos, V., Kozikowski, A.
Format: Journal Article
Published: American Chemical Society 2013
Online Access:http://hdl.handle.net/20.500.11937/3603