Identification of residues involved in NS2 homodimerization and elucidation of their impact on the HCV life cycle

The NS2 protein of hepatitis C virus (HCV) plays a critical role in virus morphogenesis and infectivity. The crystal structure of the C-terminus of the NS2 protein (NS2 Pro) from the H77 strain indicates that NS2 Pro forms a homodimer. In this study,...

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Bibliographic Details
Main Authors: Gorzin, A., Ramsland, Paul, Tachedjian, G., Gowans, E.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/35882