Arachidonic acid actions on functional integrity and attenuation of the negative effects of palmitic acid in a clonal pancreatic ß-cell line
Chronic exposure of pancreatic β-cells to saturated non-esterified fatty acids can lead to inhibition of insulin secretion and apoptosis. Several previous studies have demonstrated that saturated fatty acids such as PA (palmitic acid) are detrimental to β-cell function compared with unsaturated fatt...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Published: |
Portland Press Ltd.
2011
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/3568 |