Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5+ stem cells

Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5+ stem cells

© 2015 The Authors. The mammalian adult small intestinal epithelium is a rapidly self-renewing tissue that is maintained by a pool of cycling stem cells intermingled with Paneth cells at the base of crypts. These crypt base stem cells exclusively express Lgr5 and require Wnt3 or, in its absence, Wnt...

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Bibliographic Details
Main Authors: Flanagan, D., Phesse, T., Barker, N., Schwab, R., Amin, N., Malaterre, J., Stange, D., Nowell, C., Currie, S., Saw, J., Beuchert, E., Ramsay, R., Sansom, O., Ernst, M., Clevers, H., Vincan, Elizabeth
Format: Journal Article
Published: Cell Press 2015
Online Access:http://hdl.handle.net/20.500.11937/35609

Internet

http://hdl.handle.net/20.500.11937/35609

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