ADAM28 is elevated in humans with the metabolic syndrome and is a novel sheddase of human tumour necrosis factor-a

ADAM28 is elevated in humans with the metabolic syndrome and is a novel sheddase of human tumour necrosis factor-a

Metalloproteinases are implicated in cleaving numerous proinflammatory mediators from the cell surface. Interestingly, the elevated levels of tumour necrosis factor-α (TNF-α) have been associated with the metabolic syndrome. We aimed to ascertain whether the human metalloproteinase ADAM28 correlates...

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Bibliographic Details
Main Authors: Jowett, J., Okada, Y., Leedman, P., Curran, J., Johnson, M., Moses, Eric, Goring, H., Mochizuki, S., Blangero, J., Stone, L., Allen, H., Mitchell, C., Matthews, V.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/34989

Internet

http://hdl.handle.net/20.500.11937/34989

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