CD4 + T-cell deficiency in HIV patients responding to antiretroviral therapy is associated with increased expression of interferon-stimulated genes in CD4 + T cells

Most patients with human immunodeficiency virus (HIV) who remain CD4 + T-cell deficient on antiretroviral therapy (ART) exhibit marked immune activation. As CD4 + T-cell activation may be mediated by microbial translocation or interferon-alpha (IFN-a), we examined these factors in HIV patients with...

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Bibliographic Details
Main Authors: Fernandez, S., Tanaskovic, S., Helbig, K., Rajasuriar, R., Kramski, M., Murray, J., Beard, M., Purcell, D., Lewin, S., Price, Patricia, French, M.
Format: Journal Article
Published: 2011
Online Access:http://hdl.handle.net/20.500.11937/3445