The role of the cysteine-rich domain and netrin-like domain of secreted frizzled-related protein 4 in angiogenesis inhibition in vitro
Secreted frizzled-related protein 4 (sFRP4) is a Wnt signaling antagonist. Classically, sFRP4 antagonizes the canonical Wnt signaling pathway, resulting in decreased cellular proliferation and increased apoptosis. Recent research from our laboratory has established that sFRP4 inhibits angiogenesis b...
| Main Authors: | Longman, D., Arfuso, F., Viola, H., Hool, L., Dharmarajan, Arunasalam |
|---|---|
| Format: | Journal Article |
| Published: |
Cognizant Communication Corp.
2012
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/33951 |
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