The role of the cysteine-rich domain and netrin-like domain of secreted frizzled-related protein 4 in angiogenesis inhibition in vitro

The role of the cysteine-rich domain and netrin-like domain of secreted frizzled-related protein 4 in angiogenesis inhibition in vitro

Secreted frizzled-related protein 4 (sFRP4) is a Wnt signaling antagonist. Classically, sFRP4 antagonizes the canonical Wnt signaling pathway, resulting in decreased cellular proliferation and increased apoptosis. Recent research from our laboratory has established that sFRP4 inhibits angiogenesis b...

Full description

Bibliographic Details
Main Authors: Longman, D., Arfuso, F., Viola, H., Hool, L., Dharmarajan, Arunasalam
Format: Journal Article
Published: Cognizant Communication Corp. 2012
Subjects:
Secreted firzzled-related protein 4 (sFRP4)
Apoptosis
Calcium signaling
Angiogenesis
Online Access:http://hdl.handle.net/20.500.11937/33951

Internet

http://hdl.handle.net/20.500.11937/33951

Similar Items