Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report molecular profiling of 230 resected lung adenocarcinomas using messenger RNA, microRNA and DNA sequencing integrated with copy number, methylation and proteomic analyses. High rates of somatic mutation were see...

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Bibliographic Details
Main Authors: Collisson, E., Campbell, J., Brooks, A., Berger, A., Lee, W., Chmielecki, J., Beer, D., Cope, L., Creighton, C., Danilova, L., Ding, L., Getz, G., Hammerman, P., Hayes, D., Hernandez, B., Herman, J., Heymach, J., Jurisica, I., Kucherlapati, R., Kwiatkowski, D., Ladanyi, M., Robertson, G., Schultz, N., Shen, R., Sinha, R., Sougnez, C., Tsao, M., Travis, W., Weinstein, J., Wigle, D., Wilkerson, M., Chu, A., Cherniack, A., Hadjipanayis, A., Rosenberg, M., Weisenberger, D., Laird, P., Radenbaugh, A., Ma, S., Stuart, J., Byers, L., Baylin, S., Govindan, R., Meyerson, M., Gabriel, S., Cibulskis, K., Kim, J., Stewart, C., Lichtenstein, L., Lander, E., Lawrence, M., Getz, E., Fulton, R., Fulton, L., McLellan, M., Wilson, R., Ye, K., Fronick, C., Maher, C., Miller, C., Wendl, M., Cabanski, C., Mardis, E., Wheeler, D., Balasundaram, M., Butterfield, Y., Carlsen, R., Chuah, E., Dhalla, N., Guin, R., Hirst, C., Lee, D., Li, H., Mayo, M., Moore, R., Mungall, A., Schein, J., Sipahimalani, P., Tam, A., Varhol, Richard, Robertson, A., Wye, N., Thiessen, N., Holt, R., Jones, S., Marra, M., Imielinski, M., Onofrio, R., Hodis, E., Zack, T., Helman, E.
Format: Journal Article
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/20.500.11937/33734