Bile acids destabilise HIF-1a and promote anti-tumour phenotypes in cancer cell models.

BACKGROUND: The role of the microbiome has become synonymous with human health and disease. Bile acids, as essential components of the microbiome, have gained sustained credibility as potential modulators of cancer progression in several disease models. At physiological concentrations, bile acids ap...

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Bibliographic Details
Main Authors: Phelan, J., Reen, F., Dunphy, N., O'Connor, R., O'Gara, Fergal
Format: Journal Article
Published: 2016
Online Access:http://hdl.handle.net/20.500.11937/33390