A high-throughput screen to identify novel calcineurin inhibitors

Calcineurin is a eukaryotic protein phosphatase important for many signalling and developmental processes in cells. Inhibitors of this enzyme are used clinically and there is interest in identifying novel inhibitors for therapeutic applications. This report describes a high-throughput assay that can...

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Bibliographic Details
Main Authors: Margassery, L., Kennedy, J., O'Gara, Fergal, Dobson, A., Morrissey, J.
Format: Journal Article
Published: Elsevier Inc 2012
Online Access:http://hdl.handle.net/20.500.11937/33306