Systems genetics of the nuclear factor-?B signal transduction network. I. Detection of several quantitative trait loci potentially relevant to aging

Systems genetics of the nuclear factor-?B signal transduction network. I. Detection of several quantitative trait loci potentially relevant to aging

A theory of aging holds that senescence is caused by a dysregulated nuclear factor kappa B (NF-κB) signal transduction network (STN). We adopted a systems genetics approach in our study of the NF-κB STN. Ingenuity Pathways Analysis (IPA) was used to identify gene/gene product interactions between NF...

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Bibliographic Details
Main Authors: Diego, V., Curran, J., Charlesworth, J., Peralta, J., Voruganti, V., Cole, S., Dyer, T., Johnson, M., Moses, Eric, Göring, H., Williams, J., Comuzzie, A., Almasy, L., Blangero, J., Williams-Blangero, S.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/33281

Internet

http://hdl.handle.net/20.500.11937/33281

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