The synthesis and degradation of collagenase-degradable poly(2-hydroxyethylmethacrylate)-based hydrogels and sponges for potential applications as scaffolds in tissue engineering

The synthesis and degradation of collagenase-degradable poly(2-hydroxyethylmethacrylate)-based hydrogels and sponges for potential applications as scaffolds in tissue engineering

A collagenase-cleavable peptide-based crosslinking agent was synthesized and was incorporated into PHEMA sponges, and P[HEMA-co-MeO-PEGMA] gels and sponges [HEMA 2-hydroxyethyl methacrylate, PHEMA = poly(2-hydroxyethyl methacrylate), MeO-PEGMA=poly(ethylene glycol) monomethyl ether methacrylate]. P...

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Bibliographic Details
Main Authors: Paterson, S., Shadforth, A., Brown, David, Madden, P., Chirila, T., Baker, M.
Format: Journal Article
Published: Elsevier Science 2012
Subjects:
PHEMA
Collagenase
Enzymatic biodegradation
Functionalized peptides
Online Access:http://hdl.handle.net/20.500.11937/33183

Internet

http://hdl.handle.net/20.500.11937/33183

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