Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

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Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

Background: Functional loss of blood–brain barrier (BBB) is suggested to be pivotal to pathogenesis and pathology of vascular-based neurodegenerative disorders such as Alzheimer’s disease. We recently reported in wild-type mice maintained on standard diets, progressive deterioration of capillary fun...

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Bibliographic Details
Main Authors:	Elahy, Mina, Jackaman, Connie, Mamo, John, Lam, V., Dhaliwal, S., Giles, C., Nelson, Delia, Takechi, Ryu
Format:	Journal Article
Published:	BioMed Central Ltd. 2015
Online Access:	http://hdl.handle.net/20.500.11937/3264

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