How Do Fatty Acids Cause Allosteric Binding of Drugs to Human Serum Albumin?
Purpose. This study was undertaken to investigate how fatty acids cause the allosteric binding of drugs to human serum albumin (HSA). The influence of fatty acids on the binding of ketoprofen (KP), an NSAID, to HSA was examined by using a photoaffinity labeling technique. Methods. Ultrafiltration wa...
| Main Authors: | , |
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| Format: | Journal Article |
| Published: |
AAPS
2002
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/32173 |