Mechanisms of cisplatin-induced cell death in malignant mesothelioma cells: Role of inhibitor of apoptosis proteins (IAPs) and caspases

Malignant mesothelioma (MM) is an aggressive and highly chemoresistant tumour. Although cisplatin is used in frontline therapy of this disease treatment remains palliative at best. The biochemical pathways activated by cisplatin and the mechanisms of resistance in mesothelioma cells are poorly under...

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Bibliographic Details
Main Authors: Cregan, I., Dharmarajan, Arunasalam, Fox, S.
Format: Journal Article
Published: Spandidos Publications 2013
Online Access:http://hdl.handle.net/20.500.11937/32105