Arginine 485 of human serum albumin interacts with the benzophenone moiety of ketoprofen in the binding pocket of subdomain III A and III B

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Arginine 485 of human serum albumin interacts with the benzophenone moiety of ketoprofen in the binding pocket of subdomain III A and III B

Arylpropionic acid nonsteroidal anti-inflammatory drusg (NSAIDs) primarily bind to subdomain III A (site II) of human serum albumin (HSA). Ketoprofen (KP), an arylpropionic acid that contains a photoreactive benzophenone moiety, was used to photolabel the binding region of site II. LC/Q-TOF mass spe...

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Bibliographic Details
Main Authors:	Kaneko, K., Chuang, Victor, Ito, T., Suenaga, A., Watanabe, H., Maruyama, T., Otagiri, M.
Format:	Journal Article
Published:	Govi Verlag Pharmazeutischer Verlag GmbH 2012
Online Access:	http://hdl.handle.net/20.500.11937/31373

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