Demonstration that CobG, the monooxygenase associated with the ring contraction process of the aerobic cobalamin (vitamin B12) biosynthetic pathway, contains an Fe-S center and a mononuclear non-heme iron center
The ring contraction process that occurs during cobalamin (vitamin B12) biosynthesis is mediated via the action of two enzymes, CobG and CobJ. The first of these generates a tertiary alcohol at the C-20 position of precorrin-3A by functioning as a monooxygenase, a reaction that also forms a gamma la...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
The American Society for Biochemistry and Molecular Biology Inc
2009
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| Online Access: | http://hdl.handle.net/20.500.11937/31299 |