The adaptor protein 14-3-3 binds to the calcium-sensing receptor and attenuates receptor-mediated Rho kinase signalling

A yeast two-hybrid screen performed to identify binding partners of the CaR (calcium-sensing receptor) intracellular tail identified the adaptor protein 14-3-3? as a novel binding partner that bound to the proximal membrane region important for CaR expression and signalling. The 14-3-3? protein dire...

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Bibliographic Details
Main Authors: Arulpragasam, Ajanthy, Magno, A., Ingley, E., Brown, S., Conigrave, A., Ratajczak, T., Ward, B.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/31034