The interaction of heparin tetrasaccharides with chemokine CCL5 is modulated by sulfation pattern and pH

© 2015 by The American Society for Biochemistry and Molecular Biology, Inc. Interactions between chemokines such as CCL5 and glycosaminoglycans (GAGs) are essential for creating haptotactic gradients to guide the migration of leukocytes into inflammatory sites, and the GAGs that interact with CCL5 w...

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Bibliographic Details
Main Authors: Singh, A., Kett, W., Severin, I., Agyekum, I., Duan, J., Amster, I., Proudfoot, A., Coombe, Deidre, Woods, R.
Format: Journal Article
Published: American Society for Biochemistry and Molecular Biology Inc. 2015
Online Access:http://hdl.handle.net/20.500.11937/31026