Meningeal inflammation increases cerebrospinal fluid artemether concentrations in Papua New Guinean children treated with intramuscular artemether

QR Code

Meningeal inflammation increases cerebrospinal fluid artemether concentrations in Papua New Guinean children treated with intramuscular artemether

Although the artemisinin-associated neurotoxicity identified in vitro and in animal studies has not been confirmed clinically, only one adult study has measured cerebrospinal fluid (CSF) concentrations after administration of conventional doses. Potential artemisinin neurotoxicity could be serious i...

Full description

Bibliographic Details
Main Authors:	Manning, L., Laman, M., Page-Sharp, Madhu, Salman, S., Hwaiwhanje, I., Morep, N., Siba, P., Mueller, I., Karunajeewa, H., Davis, T.
Format:	Journal Article
Published:	American Society for Microbiology 2011
Online Access:	http://hdl.handle.net/20.500.11937/31019

Similar Items

Population Pharmacokinetics of Artemether, Lumefantrine, and Their Respective Metabolites in Papua New Guinean Children with Uncomplicated Malaria
by: Salman, S., et al.
Published: (2011)

Artemisinin-Naphthoquine versus Artemether-Lumefantrine for Uncomplicated Malaria in Papua New Guinean Children: An Open-Label Randomized Trial
by: Laman, M., et al.
Published: (2014)

Cost-effectiveness of artemisinin-naphthoquine versus artemether-lumefantrine for the treatment of uncomplicated malaria in Papua New Guinean children
by: Moore, Brioni, et al.
Published: (2017)

Artemether-lumefantrine versus artemisinin-naphthoquine in Papua New Guinean children with uncomplicated malaria: A six months post-treatment follow-up study
by: Laman, M., et al.
Published: (2015)

The effect of sickle cell genotype on the pharmacokinetic properties of artemether-lumefantrine in Tanzanian children
by: Sugiarto, S.R., et al.
Published: (2022)

PHARMACOKINETICS OF TRANSFER OF PIPERAQUINE INTO THE BREAST MILK OF PAPUA NEW GUINEAN MOTHERS
by: Moore, B., et al.
Published: (2015)

Pharmacokinetic comparison of two piperaquine-containing artemisinin combination therapies in Papua New Guinean children with uncomplicated malaria
by: Salman, S., et al.
Published: (2012)

Validation of a dried blood spot ceftriaxone assay in Papua New Guinean children with severe bacterial infections
by: Mukap, M., et al.
Published: (2018)

Effect of coadministered fat on the tolerability, safety and pharmacokinetic properties of dihydroartemisinin-piperaquine in Papua New Guinean children with uncomplicated malaria
by: Moore, Brioni, et al.
Published: (2014)

Population pharmacokinetics, tolerability, and safety of dihydroartemisinin-piperaquine and sulfadoxine-pyrimethamine-piperaquine in pregnant and nonpregnant Papua New Guinean women
by: Benjamin, J., et al.
Published: (2015)

Safety, tolerability and pharmacokinetic properties of coadministered azithromycin and piperaquine in pregnant Papua New Guinean women
by: Moore, B., et al.
Published: (2016)

Pharmacokinetic properties of single-dose primaquine in Papua New Guinean children: Feasibility of abbreviated high-dose regimens for radical cure of vivax malaria
by: Moore, Brioni, et al.
Published: (2014)

Comparison of an assumed versus measured leucocyte count in parasite density calculations in Papua New Guinean children with uncomplicated malaria
by: Laman, M., et al.
Published: (2014)

Comparative safety of artemether-lumefantrine and other artemisinin-based combinations in children: a systematic review
by: Egunsola, Oluwaseun, et al.
Published: (2013)

Risk factors for Plasmodium falciparum and Plasmodium vivax gametocyte carriage in Papua New Guinean children with uncomplicated malaria
by: Karl, S., et al.
Published: (2016)

Penicillin dried blood spot assay for use in patients receiving intramuscular benzathine penicillin G and other penicillin preparations to prevent rheumatic fever
by: Page-Sharp, Madhu, et al.
Published: (2017)

Safety and Immunogenicity of Neonatal Pneumococcal Conjugate Vaccination in Papua New Guinean Children: A Randomised Controlled Trial
by: Pomat, William, et al.
Published: (2013)

A Trial of Combination Antimalarial Therapies in Children from Papua New Guinea
by: Karunajeewa, H., et al.
Published: (2008)

Anti-inflammatory and antibacterial effects of kinos from Australian and Papua New Guinean Eucalyptus species
by: Mungkaje, Martha Yahimbu
Published: (2015)

Optimal antimalarial dose regimens for sulfadoxine-pyrimethamine with or without azithromycin in pregnancy based on population pharmacokinetic modeling
by: Salman, S., et al.
Published: (2017)

Emerging possibilities and constraints to Papua New Guinean smallholder coffee producers entering the speciality coffee market
by: Murray-Prior, Roy, et al.
Published: (2007)

Maternal Antibodies to Pneumolysin but Not to Pneumococcal Surface Protein A Delay Early Pneumococcal Carriage in High-Risk Papua New Guinean Infants
by: Francis, Jacinta, et al.
Published: (2009)

Optimal antimalarial dose regimens for chloroquine in pregnancy based on population pharmacokinetic modelling
by: Salman, S., et al.
Published: (2017)

An evaluation of patients’ adherence with hypoglycemic medications among Papua New Guineans with Type 2 Diabetes: Influencing factors
by: Pihau-Tulo, Stella, et al.
Published: (2014)

Quality of antimalarial drugs and antibiotics in Papua New Guinea: A survey of the health facility supply chain
by: Hetzel, M., et al.
Published: (2014)

Pharmacokinetic properties of sulfadoxine-pyrimethamine in pregnant women
by: Karunajeewa, H., et al.
Published: (2009)

Pharmacokinetics of Chloroquine and Monodesethylchloroquine in Pregnancy
by: Karunajeewa, H., et al.
Published: (2010)

Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: A randomized, crossover, population pharmacokinetic study in healthy adult volunteers
by: Kado, J.H., et al.
Published: (2020)

Development of a Papua New Guinean onshore carbonate reservoir: A comparative borehole image (FMI) and petrographic evaluation
by: Wilson, Moyra, et al.
Published: (2013)

High risk of early sub-therapeutic penicillin concentrations after intramuscular benzathine penicillin g injections in ethiopian children and adults with rheumatic heart disease
by: Ketema, E.B., et al.
Published: (2021)

Transfer of chloroquine and desethylchloroquine across the placenta and into milk in Melanesian mothers
by: Law, I., et al.
Published: (2008)

Retroperitoneal intramuscular haemangioma: Imaging features.
by: Hassan, H. A., et al.
Published: (2010)

Assessing the effect of meningitis prevention and treatment
by: Snelling, Thomas, et al.
Published: (2014)

Temporal changes in Plasmodium falciparum anti-malarial drug sensitivity in vitro and resistance-associated genetic mutations in isolates from Papua New Guinea
by: Koleala, T., et al.
Published: (2015)

Intermediary trading and the transformation of marketplaces in Papua New Guinea
by: Sharp, Timothy
Published: (2021)

Methicillin-resistant Staphylococcus aureus in Papua New Guinea: A community nasal colonization prevalence study
by: Laman, M., et al.
Published: (2017)

Pharmacokinetics of piperaquine transfer into the breast milk of Melanesian mothers
by: Moore, B., et al.
Published: (2015)

Intramuscular abscess causing radial nerve palsy
by: Zainol Fithri, Zairul Nizam
Published: (2007)

Analysis of the Cerebrospinal Fluid Flow in the Stenosed Aqueduct of Sylvius
by: H, Edi Azali, et al.
Published: (2011)

Syringomyelia and the fluid-structure interactions of a cerebrospinal waveguide
by: Elliott, N., et al.
Published: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ehlfdetr964ma453mpf6c33luf