Changes in Brain Transcripts Related to Alzheimer’s Disease in a Model of HFE Hemochromatosis are not Consistent with Increased Alzheimer’s Disease Risk

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Changes in Brain Transcripts Related to Alzheimer’s Disease in a Model of HFE Hemochromatosis are not Consistent with Increased Alzheimer’s Disease Risk

Iron abnormalities are observed in the brains of Alzheimer's disease (AD) patients, but it is unclear whether common disorders of systemic iron overload such as hemochromatosis alter risks of AD. We used microarrays and real-time reverse transcription-PCR to investigate changes in the brain tra...

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Bibliographic Details
Main Authors:	Johnstone, D., Graham, Ross, Trinder, D., Riveros, C., Olynyk, John, Scott, R., Moscato, P., Milward, E.
Format:	Journal Article
Published:	IOS Press 2012
Subjects:	notch signaling secretase hemochromatosis HFE Amyloid-protein precursor iron
Online Access:	http://hdl.handle.net/20.500.11937/30366

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