Potential role of PKC inhibitors in the treatment of hematological malignancies

The serine/threonine protein kinase C (PKC) family, the main target of tumor-promoting phorbol esters, is functionally associated to cell cycle regulation, cell survival, malignant transformation, and tumor angiogenesis. Although PKC isozymes represent an attractive target for novel anticancer thera...

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Bibliographic Details
Main Authors: Mischiati, C., Melloni, E., Corallini, F., Milani, D., Bergamini, C., Vaccarezza, Mauro
Format: Journal Article
Published: 2008
Online Access:http://hdl.handle.net/20.500.11937/30155