Differential effects of chemotherapeutic drugs versus the MDM-2 antagonist Nutlin-3 on cell cycle progression and induction of apoptosis in SKW6.4 lymphoblastoid B-cells
We have compared the cytotoxic/cytostatic responses of the SKW6.4 lymphoblastoid B-cells to the alkylating agent chlorambucil, the purine analog fludarabine, the non-genotoxic activator of the p53 pathway, Nutlin-3, used alone or in association with the death-inducing ligand recombinant TRAIL. Expos...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
2008
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| Online Access: | http://hdl.handle.net/20.500.11937/3008 |