Synthesis, in vitro evaluation of thymidine phosphorylase inhibitory activity, and in silico study of 1,3,5-triazin-2,4-dione and its fused analogues

Based on structural similarities with the reference compounds, a series of 1,3,5-triazin-2,4-dione and their fused analogues was designed, synthesized and their in vitro thymidine phosphorylase inhibitory potential was evaluated. The monocyclic analogues were found to be inactive. Among the differen...

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Bibliographic Details
Main Authors: Bera, H., Chui, W., Gupta, S., Dolzhenko, Anton, Sun, L.
Format: Journal Article
Published: 2013
Online Access:http://hdl.handle.net/20.500.11937/29884