Role of Focal Adhesion Tyrosine Kinases in GPVI-Dependent Platelet Activation and Reactive Oxygen Species Formation
BackgroundWe have previously shown the presence of a TRAF4/p47phox/Hic5/Pyk2 complex associated with the platelet collagen receptor, GPVI, consistent with a potential role of this complex in GPVI-dependent ROS formation. In other cell systems, NOX-dependent ROS formation is facilitated by Pyk2, whic...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Published: |
Public Library of Science
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/29835 |