Metabolomic analyses reveal profound differences in glycolytic and tricarboxylic acid cycle metabolism in glucose-responsive and -unresponsive clonal ß-cell lines
Insulin secretion from pancreatic β-cells is controlled by complex metabolic and energetic changes provoked by exposure to metabolic fuels. Perturbations in these processes lead to impaired insulin secretion, the ultimate cause of T2D (Type 2 diabetes). To increase our understanding of stimulus–secr...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Published: |
Portland Press Ltd.
2011
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/29460 |