PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma

Alterations of the cell cycle checkpoint frequently occur during hepatocarcinogenesis. Dysregulation of the phosphatidylinositol-3-kinases (PI3K) signaling pathway is believed to exert a potential oncogenic effect in hepatocellular carcinoma (HCC), ultimately promoting tumor cell proliferation. Howe...

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Bibliographic Details
Main Authors: Dituri, F., Mazzocca, A., Lupo, L., Edling, C., Azzariti, A., Antonaci, S., Falasca, Marco, Giannelli, G.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/28856