Effect of hydroxypropyl-ß-cyclodextrin complexation on the aqueous solubility and stability of artesunate

Objectives: The effect of inclusion complexes of artesunate (ART) with hydroxypropyl-ß-cyclodextrin (HP-ß-CD) at selected pH values on the phase solubility profile and stability of ART in aqueous solution was investigated. Methods: Phase solubility studies were performed in 0.20 M phosphate buffer s...

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Bibliographic Details
Main Author: Sunderland, Bruce
Format: Journal Article
Published: International Journal of Pharmacy and Pharmaceutical Sciences 2014
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/28744