The Impact of Simvastatin on Pulmonary Effectors of Pseudomonas aeruginosa Infection

The statin family of cholesterol-lowering drugs is known to have pleiotropic properties which include anti-inflammatory and immunomodulatory effects. Statins exert their pleiotropic effects by altering expression of human immune regulators including pro-inflammatory cytokines. Previously we found th...

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Bibliographic Details
Main Authors: Hennessy, E., O'Callaghan, J., Mooij, M., Legendre, C., Camacho-Vanegas, O., Camacho, S., Adams, C., Martignetti, J., O'Gara, Fergal
Format: Journal Article
Published: Public Library of Science 2014
Online Access:http://hdl.handle.net/20.500.11937/28253