Increased endoplasmic reticulum stress in decidual tissue from pregnancies complicated by fetal growth restriction with and without pre-eclampsia

Objectives: Endoplasmic reticulum (ER) stress has been implicated in both pre-eclampsia (PE) and fetal growth restriction (FGR), and is characterised by activation of three signalling branches: 1) PERK-pEIF2a, 2) ATF6 and 3) splicing of XBP1(U) into XBP1(S). To evaluate the contribution of ER stress...

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Bibliographic Details
Main Authors: Lian, I., Løset, M., Mundal, S., Fenstad, M., Johnson, M., Eide, I., Bjørge, L., Freed, K., Moses, Eric, Austgulen, R.
Format: Journal Article
Published: 2011
Online Access:http://hdl.handle.net/20.500.11937/28098