CHIP/Stub1 functions as a tumor suppressor and represses NF-?B-mediated signaling in colorectal cancer

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CHIP/Stub1 functions as a tumor suppressor and represses NF-?B-mediated signaling in colorectal cancer

The carboxyl terminus of Hsc70-interacting protein (CHIP, also named Stub1), a U-box containing E3 ubiquitin ligase, is involved in degradation of certain oncogenic proteins. Recent studies indicated that CHIP suppresses tumor progression in human cancers by targeting Src-3, hypoxia inducible factor...

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Bibliographic Details
Main Authors:	Wang, Y., Ren, F., Feng, Y., Wang, D., Jia, B., Qiu, Y., Wang, S., Yu, J., Sung, J., Xu, J., Zeps, Nikolajs, Chang, Z.
Format:	Journal Article
Published:	Oxford University Press 2014
Online Access:	http://hdl.handle.net/20.500.11937/28045

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