CHIP/Stub1 functions as a tumor suppressor and represses NF-?B-mediated signaling in colorectal cancer
The carboxyl terminus of Hsc70-interacting protein (CHIP, also named Stub1), a U-box containing E3 ubiquitin ligase, is involved in degradation of certain oncogenic proteins. Recent studies indicated that CHIP suppresses tumor progression in human cancers by targeting Src-3, hypoxia inducible factor...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Oxford University Press
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/28045 |