Oleic, Linoleic and Linolenic Acids Increase ROS Production by Fibroblasts via NADPH Oxidase Activation

QR Code

Oleic, Linoleic and Linolenic Acids Increase ROS Production by Fibroblasts via NADPH Oxidase Activation

The effect of oleic, linoleic and γ-linolenic acids on ROS production by 3T3 Swiss and Rat 1 fibroblasts was investigated. Using lucigenin-amplified chemiluminescence, a dose-dependent increase in extracellular superoxide levels was observed during the treatment of fibroblasts with oleic, linoleic a...

Full description

Bibliographic Details
Main Authors:	Hatanaka, Elaine, Dermargos, Alexandre, Hirata, Aparecida, Vinolo, Marco, Carpinelli, Angelo, Newsholme, Philip, Armelin, Hugo, Curi, Rui
Format:	Journal Article
Published:	Public Library of Science 2013
Online Access:	http://hdl.handle.net/20.500.11937/27569

Similar Items

Erratum: Comparative toxicity of oleic and linoleic acid on human lymphocytes (Life Sciences (2006) 78 (1448-1456))
by: Cury-Boaventura, M., et al.
Published: (2014)

Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic beta cell
by: Newsholme, Philip, et al.
Published: (2009)

Corrigendum to "Comparative toxicity of oleic and linoleic acid on human lymphocytes" (Life Sciences (2006) 78, (1448-1456) DOI: 10.1016/j.lfs.2005.07.038)
by: Cury-Boaventura, M., et al.
Published: (2014)

Effects of oils rich in linoleic and α-linolenic acids on fatty acid profile and gene expression in goat meat
by: Ebrahimi, Mahdi, et al.
Published: (2014)

Effects of short chain fatty acids on effector mechanisms of neutrophils
by: Vinolo, M., et al.
Published: (2009)

A proteomic analysis of the functional effects of fatty acids in NIH 3T3 fibroblasts
by: Magdalon, J., et al.
Published: (2011)

Interaction of dietary linoleic acid and α-linolenic acids with rs174547 in FADS1 gene on metabolic syndrome components among vegetarians
by: Ching, Yuan Kei, et al.
Published: (2019)

Effect of different inclusion levels of oil palm fronds on in vitro rumen fermentation pattern, fatty acid metabolism and apparent biohydrogenation of linoleic and linolenic acid.
by: Hassim, H. A., et al.
Published: (2010)

Melatonin modifies basal and stimulated insulin secretion via NADPH oxidase
by: Simões, D., et al.
Published: (2016)

Complexes of NADPH: protochlorophyllide oxidoreductase
by: El Hamouri, B., et al.
Published: (1983)

The identification of the polypeptides of NADPH-protochlorophyllide oxidoreductase
by: Oliver, Richard, et al.
Published: (1980)

Effect of dietary linolenic acid (18:3n–3)/linoleic acid (18:2n–6) ratio on growth performance, tissue fatty acid profile and histological alterations in the liver of juvenile Tor tambroides
by: Fard, Ehsan Ramezani, et al.
Published: (2014)

Molecular mechanisms of ROS production and oxidative stress in diabetes
by: Newsholme, Philip, et al.
Published: (2016)

The regulatory roles of NADPH oxidase, intra- and extra-cellular HSP70 in pancreatic islet function, dysfunction and diabetes
by: Krause, M., et al.
Published: (2015)

S-nitrosylation of NADPH oxidase regulates cell death in plant immunity
by: Yun, Byung Wook, et al.
Published: (2011)

Hydroxymethylglutaryl coA reductase (NADPH) in the latex of Hevea brasiliensis
by: Sipat, Abdullah B.
Published: (1982)

Activation of Survival and Apoptotic Signaling Pathways in Lymphocytes Exposed to Palmitic Acid
by: Takahashi, H., et al.
Published: (2011)

Mitochondrial ROS and involvement of Bcl-2 as a mitochondrial ROS regulator
by: Chong, S., et al.
Published: (2014)

Pigment epithelium-derived factor stimulates skeletal muscle glycolytic activity through NADPH oxidase-dependent reactive oxygen species production
by: Carnagarin, R., et al.
Published: (2016)

Natural bioactive compounds targeting NADPH oxidase pathway in cardiovascular diseases
by: M. Sofiullah, Siti Sarah, et al.
Published: (2023)

Persistence of Inflammatory Response to Intense Exercise in Diabetic Rats
by: Bortolon, J., et al.
Published: (2012)

Reactive oxygen and nitrogen species generation, antioxidant defenses, and β-cell function: a critical role for amino acids
by: Newsholme, Philip, et al.
Published: (2012)

Levels Of Conjugated Linoleic Acids In Kedah-Kelantan Cattle And The Cytotoxic Effects Of Selected Conjugated Linoleic Acid Isomers On Cancer Cell Lines
by: Beyene, Achenef Melaku
Published: (2009)

Conjugated Linoleic acids in cattle slaughtered for human consumption.
by: Achenef, Melaku Beyene, et al.
Published: (2011)

Study on the concentration of isooctane from oleic acid
by: Mohd Shahli, Mohd Sidek
Published: (2008)

Alpha-linolenic acid supplementation in Tris extender can improve frozen–thawed bull semen quality
by: Kaka, Asmatullah, et al.
Published: (2015)

Diet high in α-linolenic acid up-regulate PPAR-α gene expression in the liver of goats
by: Ebrahimi, Mahdi, et al.
Published: (2015)

Improving quality of frozen-thawed bull spermatozoa via in vitro supplementation with alpha-linolenic and docosahexaenoic acid
by: Kaka, Asmatullah
Published: (2015)

Conjugated Linoleic Acid and other Fatty Acid Content in the Milk Fat of Mafriwal and Jersey Cows and the Antioxidant Activity of Selected Conjugated Linoleic Acids Isomers
by: Mohammed Ali, Yassir
Published: (2010)

The effect of conjugated linoleic acid on lipid metabolism in the hamster and the sheep
by: Flux, Claire Louise
Published: (2005)

Biotransformation and stereoselective synthesis of pharmaceutical molecules from linoleic acid
by: Omar, Muhammad Nor, et al.
Published: (2007)

Effects of conjugated linoleic acid adipogenic genes regulation in chickens
by: Ramiah, Suriya Kamari
Published: (2015)

Effects of conjugated linoleic acid on adipogenic genes regulation in chickens
by: Ramiah, Suriya Kumari
Published: (2015)

Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic ß-cell dysfunction
by: Michalska, M., et al.
Published: (2010)

Reaction kinetics of the catalytic esterification of oleic acid with methanol
by: Tham, San Chin
Published: (2010)

Optimisation of ammonium tartrate and glucose concentration for gamma linolenic acid production by Cunninghamella sp. 2A1.
by: Farhila Muhid,, et al.
Published: (2010)

The role of NADPH oxidase (NOX) 1 and 2 in GPVI-dependent platelet activation and thrombus formation
by: Walsh, T., et al.
Published: (2013)

Cloud Based Ros Implementation for Indoor Robot
by: Lim, Jia Zhi
Published: (2019)

NADPH oxidase mediates TNF-α-evoked in vitro brain barrier dysfunction: roles of apoptosis and time
by: Abdullah, Zuraidah, et al.
Published: (2014)

Genetic and Genomic Analysis of Rhizoctonia solani Interactions with Arabidopsis; Evidence of Resistance Mediated through NADPH Oxidases
by: Foley, R., et al.
Published: (2013)