Oleic, Linoleic and Linolenic Acids Increase ROS Production by Fibroblasts via NADPH Oxidase Activation

The effect of oleic, linoleic and γ-linolenic acids on ROS production by 3T3 Swiss and Rat 1 fibroblasts was investigated. Using lucigenin-amplified chemiluminescence, a dose-dependent increase in extracellular superoxide levels was observed during the treatment of fibroblasts with oleic, linoleic a...

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Bibliographic Details
Main Authors: Hatanaka, Elaine, Dermargos, Alexandre, Hirata, Aparecida, Vinolo, Marco, Carpinelli, Angelo, Newsholme, Philip, Armelin, Hugo, Curi, Rui
Format: Journal Article
Published: Public Library of Science 2013
Online Access:http://hdl.handle.net/20.500.11937/27569