Induction of diabetes with signs of autoimmunity in primates by the injection of multiple-low-dose streptozotocin

Induction of diabetes with signs of autoimmunity in primates by the injection of multiple-low-dose streptozotocin

Aim: To develop a preclinical large animal model of autoimmune diabetes to facilitate the translational research of autoimmune diabetes in human. Materials and methods: Nine young rhesus monkeys received multiple-low-dose (MLD) intravenous injections of streptozotocin for five consecutive days, foll...

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Bibliographic Details
Main Authors: Wei, L., Lu, Y., He, S., Jin, X., Zeng, L., Zhang, S., Chen, Younan, Tian, B., Mai, G., Yang, G., Zhang, J., Wang, L., Li, H., Markmann, J., Cheng, J., Deng, S.
Format: Journal Article
Published: 2011
Online Access:http://hdl.handle.net/20.500.11937/2751

Internet

http://hdl.handle.net/20.500.11937/2751

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