Facile synthesis, ex-vivo and in vitro screening of 3-sulfonamide derivative of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxy lic acid piperidin-1-ylamide (SR141716) a potent CB1 receptor antagonist

Facile synthesis, ex-vivo and in vitro screening of 3-sulfonamide derivative of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxy lic acid piperidin-1-ylamide (SR141716) a potent CB1 receptor antagonist

Facile synthesis of biaryl pyrazole sulfonamide derivative of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxy lic acid piperidin-1-ylamide (SR141716, 1) and an investigation of the effect of replacement of the -CO group in the compound 1 by the -SO2 group in the aminopiperid...

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Bibliographic Details
Main Authors: Kumar Srivastava, B., Soni, R., Patel, J., Jha, S., Shedage, S., Gandhi, Neha, Sairam, K., Pawar, V., Sadhwani, N., Mitra, P., Jain, M., Patel, P.
Format: Journal Article
Published: Pergamon 2008
Online Access:http://hdl.handle.net/20.500.11937/27282

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http://hdl.handle.net/20.500.11937/27282

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