Investigational ABC transporter inhibitors

Introduction: Multidrug resistance (MDR) is the main cause of failure in cancer therapy. One mechanism responsible for MDR is the active efflux of drugs by ATP-binding cassette (ABC) transporters. Several agents have been developed to block transporter-mediated drug efflux and some of these compound...

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Bibliographic Details
Main Authors: Falasca, Marco, Linton, K.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/27166